Laser Adverse Event Protocol: Pigmentary Disorders (PIH, Hypopigmentation, Scarring)

Published:

October 7, 2025


Service: Fotona SP Dynamis (Er:YAG 2940 nm / Nd:YAG 1064 nm) & StarWalker MaQX (QS 1064/532 nm ± dye 585/650 nm).

Cause / Mechanism

Pigmentary changes arise when laser energy disrupts epidermal and dermal melanocytes. Excessive fluence, wavelength mismatch, or inadequate post-procedure photoprotection can trigger post-inflammatory hyperpigmentation (PIH). Hypopigmentation occurs when melanocytes are destroyed, more common with Q-switched and ablative lasers. Scarring develops when deep dermal injury occurs. 1 2

Risk Factors

  • Patient: Fitzpatrick IV–VI (higher melanin activity), recent tanning, history of melasma or PIH.
  • Device: short-pulse, high-fluence treatments; repeated passes.
  • Operator: insufficient test spots, lack of parameter titration.
  • Environment: unprotected UV exposure post-treatment. 2 3

Signs & Symptoms

  • PIH: patchy brown macules/papules within 1–3 weeks post-procedure.
  • Hypopigmentation: discrete or confluent white patches, may persist months.
  • Scarring: textural change, atrophy, hypertrophic/keloid formation. 4 5

Prevention

  • Careful parameter adjustment according to skin type (lower fluence in darker types).
  • Strict pre- and post-treatment photoprotection (broad-spectrum SPF 50+). 6
  • Educate patients on sun avoidance, especially 2–4 weeks post-procedure.
  • Consider prophylactic hydroquinone or retinoids in high-risk PIH patients (per dermatology guidance). 7

Management Protocol

Post-Inflammatory Hyperpigmentation (PIH):

  • Immediate: strict photoprotection and SPF.
  • Mild: topical hydroquinone 2–4%, azelaic acid, or retinoids as tolerated. 7
  • Moderate-severe: dermatology referral for chemical peels or further topical therapies.

Hypopigmentation:

  • Observation (some cases repigment spontaneously within 6–12 months).
  • Camouflage cosmetics for cosmetic support.
  • Dermatology referral if persistent (may consider excimer laser, topical calcineurin inhibitors). 4

Scarring:

  • Early identification and referral.
  • Silicone gel/sheeting for hypertrophic scars.
  • Intralesional corticosteroid for resistant hypertrophic/keloid scars.
  • Fractional laser resurfacing may assist long-term but not acutely. 5

Follow-up & Documentation

  • Document onset, severity, and treatment steps.
  • Provide written aftercare instructions highlighting photoprotection.
  • Schedule regular reviews until resolution or referral.
  • Record incident in Laser Log; use outcomes in quality review meetings. 1 2

Sources

  1. AS/NZS 4173:2018 Safe use of lasers and intense light sources in health care., viewed 7 October 2025, https://www.standards.org.au ↩︎
  2. ARPANSA. Advice for providers: Lasers, IPL and LED for cosmetic purposes., viewed 7 October 2025, https://www.arpansa.gov.au ↩︎
  3. Australasian College of Dermatologists. Pigmentation disorders and PIH., viewed 7 October 2025, https://www.dermcoll.edu.au ↩︎
  4. DermNet NZ. Postinflammatory hyperpigmentation and hypopigmentation., viewed 7 October 2025, https://dermnetnz.org/topics/postinflammatory-hyperpigmentation ↩︎
  5. UNSW Safety. Risks of laser-induced scarring., viewed 7 October 2025, https://safety.unsw.edu.au ↩︎
  6. Cancer Council Australia. Sun protection recommendations., viewed 7 October 2025, https://www.cancer.org.au ↩︎
  7. Australasian College of Dermatologists. Hydroquinone and retinoid use in pigmentation., viewed 7 October 2025, https://www.dermcoll.edu.au ↩︎
Author:
Dr. Bart Scanlon
Medical Practitioner
Medical Registration Number: MED00019402249

Newcastle Cosmetic Doctor

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