1. Purpose
Provide a safe, evidence-based framework for botulinum toxin type A (BoNT-A) treatment of horizontal forehead lines (frontalis) consistent with Australian medical governance and current clinical consensus. 1
2. Scope
Applies to AHPRA-registered practitioners performing or supervising anti-wrinkle injections to the forehead (frontalis region), including assessment, dosing, consent, and follow-up. 1
3. Governance (Australia)
Requires a face-to-face prescriber consultation, compliance with TGA advertising rules, and clinical documentation according to NSQHS governance standards. 1
4. Regional Anatomy & Injection Mapping
The frontalis muscle elevates the eyebrows and produces horizontal lines. Consensus technique: multiple small injection points across the upper two-thirds of the forehead, maintaining at least 2 cm above the brow to avoid brow ptosis. 4
5. Dosing (Australian Product Information)
Typical Australian-approved total dose: 10–20 Units of onabotulinumtoxinA (or equivalent) distributed across 4–8 injection sites; dosing must be individualised per muscle strength, gender, and prior response. 5
6. Contraindications
Defer in pregnancy, breastfeeding, local infection, or significant neuromuscular disorders. Review all medical and medication history before injection. 2
7. Informed Consent & Risks
Explain expected outcomes (softening of lines, not full removal), possible bruising, heaviness, or brow ptosis from diffusion, and need for repeat treatment every 3–6 months. 1
8. Post-Treatment Care
Stay upright for at least four hours; avoid rubbing, vigorous exercise, saunas, or facials for 24–48 hours; reassess at two weeks for symmetry and satisfaction. 2
9. Adverse Events & Management
Brow ptosis may respond to cautious use of apraclonidine 0.5 % drops; review and document outcome. Bruising is self-limiting; reassure and monitor. 6
10. Documentation & Audit
Record prescriber, injector, product, batch, expiry, total dose, injection map, consent, and review notes. Maintain annual audit and at least 20 hours CPD in cosmetic injectables. 3
Sources
- AHPRA 2025, Guidelines for Cosmetic Medical and Surgical Procedures, Canberra., viewed 04 November 2025, https://www.ahpra.gov.au/News/2025-09-02-New-guidelines-for-cosmetic-procedures.aspx ↩
- Queensland Health 2024, Beginner’s Guide to Cosmetic Injectables, Brisbane., viewed 04 November 2025, https://www.health.qld.gov.au/newsroom/news/beginner-friendly-guide-to-cosmetic-injectables ↩
- Australian Commission on Safety and Quality in Health Care (ACSQHC) 2023, NSQHS Standards – Medication Safety, Sydney., viewed 04 November 2025, https://www.safetyandquality.gov.au ↩
- Ascher B et al. 2024, International Consensus Recommendations on the Aesthetic Usage of Ready-to-Use AbobotulinumtoxinA (Alluzience), Aesthetic Surgery Journal, 44(2):192–202., viewed 04 November 2025, https://academic.oup.com/asj/article-abstract/44/2/192/7231033 ↩
- Therapeutic Goods Administration (TGA) 2023, Australian Product Information – Letybo and Relfydess for Frontalis Lines., viewed 04 November 2025, https://www.tga.gov.au ↩
- De Boulle K, Carruthers A, Solish N, Carruthers J, Phillipp-Dormston WG, Fagien S, Sangha S, Silberberg M, Mao C., OnabotulinumtoxinA Treatment for Moderate to Severe Forehead Lines: A Review. (2020) Plast Reconstr Surg Glob Open, viewed 04 November 2025, https://pmc.ncbi.nlm.nih.gov/articles/PMC7253259/ ↩


