1. Purpose
Provide a safe, evidence-based framework for botulinum toxin type A (BoNT-A) treatment of bunny lines (nasalis wrinkles) consistent with Australian medical governance and international clinical consensus. 1
2. Scope
Applies to AHPRA-registered practitioners performing or supervising cosmetic injections targeting the nasalis muscle for reduction of dynamic nasal wrinkles. 1
3. Governance (Australia)
Requires a face-to-face prescriber consultation, compliance with TGA advertising restrictions, and documentation consistent with NSQHS medication-safety standards. 1
4. Regional Anatomy & Injection Mapping
Bunny lines form from hyperactivity of the transverse nasalis and occasionally the levator labii superioris alaeque nasi. Consensus technique: inject 1–2 U per side along the upper nasal sidewall, keeping 1 cm lateral to the nasal bridge to avoid diffusion. 4
5. Dosing (Guideline Based)
Typical total dose: 2–4 U per side (4–8 U total). Adjust per anatomy and muscle bulk; follow recognised consensus guidance and Australian regulatory requirements. 5
6. Contraindications
Defer in pregnancy, breastfeeding, local infection, or significant neuromuscular disorders. Review medical and allergy history before treatment. 2
7. Informed Consent & Risks
Explain realistic outcomes (softening, not elimination), small risk of asymmetry, mild bruising, or transient nasal obstruction from diffusion, and the need for repeat treatment every 3–4 months. 1
8. Post-Treatment Care
Remain upright ≥ 4 h; avoid rubbing or massaging the nose, strenuous exercise, or saunas for 24–48 h; re-evaluate after 2 weeks. 2
9. Adverse Events & Management
Over-diffusion may cause mild flattening of nasal flare or temporary nasal stuffiness. Bruising is self-limiting; advise cold compress and reassurance. 6
10. Documentation & Audit
Record prescriber, injector, product, batch, expiry, dose, injection sites, consent, and follow-up notes. Maintain annual audits and at least 20 hours CPD per year. 3
Sources
- AHPRA 2025, Guidelines for Cosmetic Medical and Surgical Procedures, Canberra., viewed 04 November 2025, https://www.ahpra.gov.au/News/2025-09-02-New-guidelines-for-cosmetic-procedures.aspx ↩
- Queensland Health 2024, Beginner’s Guide to Cosmetic Injectables, Brisbane., viewed 04 November 2025, https://www.health.qld.gov.au/newsroom/news/beginner-friendly-guide-to-cosmetic-injectables ↩
- Australian Commission on Safety and Quality in Health Care (ACSQHC) 2023, NSQHS Standards – Medication Safety, Sydney., viewed 04 November 2025, https://www.safetyandquality.gov.au ↩
- American Society for Dermatologic Surgery (ASDS) 2022, Resident Training Guide: Dose, Dilution and Injection Technique for Botulinum Toxin Type A in Cosmetic Practice, ASDS Education Series., viewed 04 November 2025, https://www.asds.net/Portals/0/PDF/Resident-Kit-Allergan-BOTOX-Cosmetic-Dosing-Reconstitution-Tool.pdf ↩
- AbbVie Medical Information 2024, Highlights of Prescribing Information – Botulinum Toxin Type A for Cosmetic Use (Glabellar and Periorbital Lines), US Label Reference., viewed 04 November 2025, https://www.rxabbvie.com/pdf/botox-cosmetic_pi.pdf ↩
- Yi KH, Lee JH, Hu HW, Kim HJ., Novel Anatomical Guidelines on Botulinum Neurotoxin Injection for Wrinkles in the Nose Region. Toxins (Basel). 2022., viewed 04 November 2025, https://pmc.ncbi.nlm.nih.gov/articles/PMC9144745/ ↩


